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gene exp cspg4 rn00578849 m1  (Thermo Fisher)
85
Thermo Fisher gene exp cspg4 rn00578849 m1
A) Representative trace from whole-cell patch clamp electrophysiology of a primary rat OPC in culture. The top of the graph is the stimulation trace showing the 300 ms stimulation trace with 0.4 µm step-wise increases in membrane displacement using a glass stimulation rod. The bottom portion of the graph shows the current (pA) trace at each stimulation. 13 of the 14 tested cells showed detectable MA currents. Scale bar: 10 μm B) Maximal current (Imax) for each cell in response to indentation stimulation N = 2 animals, 14 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . C) Inactivation time constant for each cell responsive to indentation stimulation N = 2 animals, 13 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . D) qRT-PCR of Piezo1 , Tmem63a , Mag , and <t>Cspg4</t> in cultured rat OLs during differentiation (0-192 h). Values are normalized to the transcript’s highest expression value during differentiation N = 3 animals, 3 independent cell isolations. E) Western blot analysis of PIEZO1-tdTOMATO, PDGFRA, MBP, and ACTB expression in Piezo1 tdT/tdT and Piezo1 Wt/Wt control murine OPCs and OLs at 24-72h differentiation. F) Quantification of tdTOMATO intensity relative to ACTB in western blots. N = 3 animals per genotype, 3 independent cell isolations. Red dots indicate the data points corresponding to the example image in E.
Gene Exp Cspg4 Rn00578849 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/Gene+Exp%2E+Cspg4%2C+Rn00578849_m1/bio_rxiv__64898__2026__04__23__720488-245-14-16
Average 85 stars, based on 1 article reviews
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cspg4 cre esr1 mice  (Jackson Laboratory)
86
Jackson Laboratory cspg4 cre esr1 mice
A) Representative trace from whole-cell patch clamp electrophysiology of a primary rat OPC in culture. The top of the graph is the stimulation trace showing the 300 ms stimulation trace with 0.4 µm step-wise increases in membrane displacement using a glass stimulation rod. The bottom portion of the graph shows the current (pA) trace at each stimulation. 13 of the 14 tested cells showed detectable MA currents. Scale bar: 10 μm B) Maximal current (Imax) for each cell in response to indentation stimulation N = 2 animals, 14 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . C) Inactivation time constant for each cell responsive to indentation stimulation N = 2 animals, 13 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . D) qRT-PCR of Piezo1 , Tmem63a , Mag , and <t>Cspg4</t> in cultured rat OLs during differentiation (0-192 h). Values are normalized to the transcript’s highest expression value during differentiation N = 3 animals, 3 independent cell isolations. E) Western blot analysis of PIEZO1-tdTOMATO, PDGFRA, MBP, and ACTB expression in Piezo1 tdT/tdT and Piezo1 Wt/Wt control murine OPCs and OLs at 24-72h differentiation. F) Quantification of tdTOMATO intensity relative to ACTB in western blots. N = 3 animals per genotype, 3 independent cell isolations. Red dots indicate the data points corresponding to the example image in E.
Cspg4 Cre Esr1 Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/cre+cspg4+ng2/pmc08963131-273-0-15
Average 86 stars, based on 1 article reviews
cspg4 cre esr1 mice - by Bioz Stars, 2026-09
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female cspg4 ng2 cre mice  (Jackson Laboratory)
86
Jackson Laboratory female cspg4 ng2 cre mice
A) Representative trace from whole-cell patch clamp electrophysiology of a primary rat OPC in culture. The top of the graph is the stimulation trace showing the 300 ms stimulation trace with 0.4 µm step-wise increases in membrane displacement using a glass stimulation rod. The bottom portion of the graph shows the current (pA) trace at each stimulation. 13 of the 14 tested cells showed detectable MA currents. Scale bar: 10 μm B) Maximal current (Imax) for each cell in response to indentation stimulation N = 2 animals, 14 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . C) Inactivation time constant for each cell responsive to indentation stimulation N = 2 animals, 13 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . D) qRT-PCR of Piezo1 , Tmem63a , Mag , and <t>Cspg4</t> in cultured rat OLs during differentiation (0-192 h). Values are normalized to the transcript’s highest expression value during differentiation N = 3 animals, 3 independent cell isolations. E) Western blot analysis of PIEZO1-tdTOMATO, PDGFRA, MBP, and ACTB expression in Piezo1 tdT/tdT and Piezo1 Wt/Wt control murine OPCs and OLs at 24-72h differentiation. F) Quantification of tdTOMATO intensity relative to ACTB in western blots. N = 3 animals per genotype, 3 independent cell isolations. Red dots indicate the data points corresponding to the example image in E.
Female Cspg4 Ng2 Cre Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/cre+cspg4+ng2/pm42113962-186-0-4
Average 86 stars, based on 1 article reviews
female cspg4 ng2 cre mice - by Bioz Stars, 2026-09
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cspg4 dsred transgenic mice  (Jackson Laboratory)
86
Jackson Laboratory cspg4 dsred transgenic mice
A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; <t>CSPG4</t> :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.
Cspg4 Dsred Transgenic Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/cxcl12+dsred+mice/bio_rxiv__64898__2026__03__13__711636-193-7-18
Average 86 stars, based on 1 article reviews
cspg4 dsred transgenic mice - by Bioz Stars, 2026-09
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rabbit polyclonal  (Atlas Antibodies)
93
Atlas Antibodies rabbit polyclonal
A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; <t>CSPG4</t> :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.
Rabbit Polyclonal, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/Anti-CSPG4/pm41794948-253-6-8
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rabbit polyclonal - by Bioz Stars, 2026-09
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anti cspg4  (Atlas Antibodies)
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Atlas Antibodies anti cspg4
A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; <t>CSPG4</t> :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.
Anti Cspg4, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/Anti-CSPG4/pm41794948-253-4-8
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anti cspg4 - by Bioz Stars, 2026-09
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mouse anti cspg4  (Santa Cruz Biotechnology)
94
Santa Cruz Biotechnology mouse anti cspg4
A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; <t>CSPG4</t> :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.
Mouse Anti Cspg4, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/NG2+Antibody/pmc12915979-76-23-25
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gene exp cspg4 mm00507257 m1  (Thermo Fisher)
97
Thermo Fisher gene exp cspg4 mm00507257 m1
A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; <t>CSPG4</t> :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.
Gene Exp Cspg4 Mm00507257 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cspg4/Gene+Exp%2E+Cspg4%2C+Mm00507257_m1/pm41709465-407-32-7
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Image Search Results


A) Representative trace from whole-cell patch clamp electrophysiology of a primary rat OPC in culture. The top of the graph is the stimulation trace showing the 300 ms stimulation trace with 0.4 µm step-wise increases in membrane displacement using a glass stimulation rod. The bottom portion of the graph shows the current (pA) trace at each stimulation. 13 of the 14 tested cells showed detectable MA currents. Scale bar: 10 μm B) Maximal current (Imax) for each cell in response to indentation stimulation N = 2 animals, 14 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . C) Inactivation time constant for each cell responsive to indentation stimulation N = 2 animals, 13 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . D) qRT-PCR of Piezo1 , Tmem63a , Mag , and Cspg4 in cultured rat OLs during differentiation (0-192 h). Values are normalized to the transcript’s highest expression value during differentiation N = 3 animals, 3 independent cell isolations. E) Western blot analysis of PIEZO1-tdTOMATO, PDGFRA, MBP, and ACTB expression in Piezo1 tdT/tdT and Piezo1 Wt/Wt control murine OPCs and OLs at 24-72h differentiation. F) Quantification of tdTOMATO intensity relative to ACTB in western blots. N = 3 animals per genotype, 3 independent cell isolations. Red dots indicate the data points corresponding to the example image in E.

Journal: bioRxiv

Article Title: PIEZOs regulate oligodendrocyte sheath formation, expansion, and myelination potential

doi: 10.64898/2026.04.23.720488

Figure Lengend Snippet: A) Representative trace from whole-cell patch clamp electrophysiology of a primary rat OPC in culture. The top of the graph is the stimulation trace showing the 300 ms stimulation trace with 0.4 µm step-wise increases in membrane displacement using a glass stimulation rod. The bottom portion of the graph shows the current (pA) trace at each stimulation. 13 of the 14 tested cells showed detectable MA currents. Scale bar: 10 μm B) Maximal current (Imax) for each cell in response to indentation stimulation N = 2 animals, 14 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . C) Inactivation time constant for each cell responsive to indentation stimulation N = 2 animals, 13 cells, 2 independent cell isolations. The red data point is associated with the representative trace in . D) qRT-PCR of Piezo1 , Tmem63a , Mag , and Cspg4 in cultured rat OLs during differentiation (0-192 h). Values are normalized to the transcript’s highest expression value during differentiation N = 3 animals, 3 independent cell isolations. E) Western blot analysis of PIEZO1-tdTOMATO, PDGFRA, MBP, and ACTB expression in Piezo1 tdT/tdT and Piezo1 Wt/Wt control murine OPCs and OLs at 24-72h differentiation. F) Quantification of tdTOMATO intensity relative to ACTB in western blots. N = 3 animals per genotype, 3 independent cell isolations. Red dots indicate the data points corresponding to the example image in E.

Article Snippet: Piezo1 (ThermoFisher, Rn01432593_m1) Piezo2 (ThermoFisher, Rn01491821_m1) Tmem63a (ThermoFisher, Rn01415187_m1) Mag (ThermoFisher, Rn01457782_m1) Cspg4 (ThermoFisher, Rn00578849_m1) GAPDH (ThermoFisher, Rn0177563_g1)

Techniques: Patch Clamp, Membrane, Quantitative RT-PCR, Cell Culture, Expressing, Western Blot, Control

A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; CSPG4 :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.

Journal: bioRxiv

Article Title: Early demyelination by off-target complement injury in a mouse model of neuromyelitis optica

doi: 10.64898/2026.03.13.711636

Figure Lengend Snippet: A. Individual time frames showing microglial activation ( CX3CR1 :GFP) in the presence/context of AQP4-IgG and complement, characterized by process extension and the formation of engulfment protrusions ( left ). In control experiments, microglia maintained their morphology without process extension ( right ). Scale bars 30 µm. B. Oligodendrocyte precursor cells (OPCs; CSPG4 :DsRed) remain mostly unaffected in both AQP4-IgG (left) or control conditions ( right ). Dashed white boxes indicate the cells shown in panel C. C. Fraction of surviving OPCs at 6-hour following r-Ctr-IgG (N = 4 mice) or rAQP4-IgG (N = 3 mice) treatment. Representative OPCs from each experiment are shown in the insets. The yellow arrowhead indicates a pericyte along the vasculature, identifiable by its elongated cell body, in contrast to the characteristically round soma of OPCs. Data are shown as mean ± SEM.

Article Snippet: Oligodendrocyte precursor cells (OPCs) were imaged in CSPG4 :DsRed transgenic mice ( Zhu et al ., 2008 ; JAX: 8241).

Techniques: Activation Assay, Control